Tissue factor activity is increased in human endothelial cells cultured under elevated static pressure

We tested the hypothesis that elevated blood pressure, a known stimulus for vascular remodeling and an independent risk factor for the development of atherosclerotic disease, can modulate basal and cytokine-induced tissue factor (TF; CD142) expression in cultured human endothelial cells (EC).

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Bibliographic Details
Published in:American Journal of Physiology: Cell Physiology 1999-08, Vol.46 (2), p.C233-C242
Main Authors: SILVERMAN, M. D, WATERS, C. R, HAYMAN, G. T, WIGBOLDUS, J, SAMET, M. M, LELKES, P. I
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood vessels and receptors
Cells
Disease
Fundamental and applied biological sciences. Psychology
Membranes
Plasma
Ribonucleic acid
RNA
Tissues
Tumors
Vertebrates: cardiovascular system
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Description
Summary:We tested the hypothesis that elevated blood pressure, a known stimulus for vascular remodeling and an independent risk factor for the development of atherosclerotic disease, can modulate basal and cytokine-induced tissue factor (TF; CD142) expression in cultured human endothelial cells (EC).
ISSN:0363-6143
1522-1563