Ovine male genital duct epithelial cells differentiate in vitro and express functional CFTR and ENaC

To investigate the biology of the male genital duct epithelium, we have established cell cultures from the ovine vas deferens and epididymis epithelium. These cells develop tight junctions, high transepithelial electrical resistance, and a lumen-negative transepithelial potential difference as a sig...

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Bibliographic Details
Published in:American Journal of Physiology: Cell Physiology 2000-05, Vol.47 (5), p.C885-C894
Main Authors: BERTOG, M, SMITH, D. J, BIELFELD-ACKERMANN, A, BASSETT, J, FERGUSON, D. J. P, KORBMACHER, C, HARRIS, A
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cystic fibrosis
Fundamental and applied biological sciences. Psychology
Males
Mammalian male genital system
Morphology. Physiology
Reproductive system
Sheep
Sodium
Vertebrates: reproduction
Online Access:Get full text
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Summary:To investigate the biology of the male genital duct epithelium, we have established cell cultures from the ovine vas deferens and epididymis epithelium. These cells develop tight junctions, high transepithelial electrical resistance, and a lumen-negative transepithelial potential difference as a sign of active transepithelial ion transport.
ISSN:0363-6143
1522-1563