Developmental changes in ryanodine- and IP3-sensitive Ca2+ pools in ovine basilar artery

To explore the hypothesis that cerebrovascular maturation alters ryanodine- and inositol 1,4,5-trisphosphate (IP3)-sensitive Ca2+ pool sizes, we measured total intracellular Ca2+ with (45)Ca and the fractions of intracellular Ca2+ released by IP3 and/or caffeine in furaptra-loaded permeabilized basi...

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Published in:American Journal of Physiology: Cell Physiology 2001-12, Vol.50 (6), p.C1785-C1796
Main Authors: NAULI, S. M, WILLIAMS, J. M, AKOPOV, S. E, ZHANG, L, PEARCE, W. J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Brain
Calcium
Cell physiology
Fundamental and applied biological sciences. Psychology
Molecular and cellular biology
Muscle contraction
Sheep
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container_issue 6
container_start_page C1785
container_title American Journal of Physiology: Cell Physiology
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creator NAULI, S. M
WILLIAMS, J. M
AKOPOV, S. E
ZHANG, L
PEARCE, W. J
description To explore the hypothesis that cerebrovascular maturation alters ryanodine- and inositol 1,4,5-trisphosphate (IP3)-sensitive Ca2+ pool sizes, we measured total intracellular Ca2+ with (45)Ca and the fractions of intracellular Ca2+ released by IP3 and/or caffeine in furaptra-loaded permeabilized basilar arteries from nonpregnant adult and term fetal (139-141 days) sheep.
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source American Physiological Society Free
subjects Biological and medical sciences
Brain
Calcium
Cell physiology
Fundamental and applied biological sciences. Psychology
Molecular and cellular biology
Muscle contraction
Sheep
title Developmental changes in ryanodine- and IP3-sensitive Ca2+ pools in ovine basilar artery
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