Expression of endoplasmic reticulum stress proteins during skeletal muscle disuse atrophy

Disuse atrophy of skeletal muscle leads to an upregulation of genes encoding sarcoplasmic reticulum (SR) caleium-handling proteins. Because many of the proteins that are induced with endoplasmic reticulum (ER) stress are ER calcium-handling proteins, we sought to determine whether soleus muscle atro...

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Bibliographic Details
Published in:American Journal of Physiology: Cell Physiology 2001-10, Vol.50 (4), p.C1285-C1290
Main Authors: HUNTER, R. Bridge, MITCHELL-FELTON, Heather, ESSIG, David A, KANDARIAN, Susan C
Format: Article
Language:English
Subjects:
Biological and medical sciences
Calcium
Fundamental and applied biological sciences. Psychology
Glucose
Muscular system
Plasma
Proteins
Skeletal system
Striated muscle. Tendons
Vertebrates: osteoarticular system, musculoskeletal system
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Summary:Disuse atrophy of skeletal muscle leads to an upregulation of genes encoding sarcoplasmic reticulum (SR) caleium-handling proteins. Because many of the proteins that are induced with endoplasmic reticulum (ER) stress are ER calcium-handling proteins, we sought to determine whether soleus muscle atrophy was associated with a prototypical ER stress response.
ISSN:0363-6143
1522-1563