Differences in contractile protein content and isoforms in phasic and tonic smooth muscles

The basis of tonic vs. phasic contractile phenotypes of visceral smooth muscles is poorly understood. We used gel electrophoresis and quantitative scanning densitometry to measure the content and isoform composition of contractile proteins in opossum lower esophageal sphincter (LES), to represent to...

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Bibliographic Details
Published in:American Journal of Physiology: Cell Physiology 1998-09, Vol.44 (3), p.C684-C692
Main Authors: SZYMANSKI, P. T, CHACKO, T. K, ROVNER, A. S, GOYAL, R. K
Format: Article
Language:English
Subjects:
Biochemistry
Biological and medical sciences
Cellular biology
Fundamental and applied biological sciences. Psychology
Mouth. Exocrine and endocrine salivary glands. Teeth. Esophagus
Muscular system
Proteins
Vertebrates: digestive system
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Summary:The basis of tonic vs. phasic contractile phenotypes of visceral smooth muscles is poorly understood. We used gel electrophoresis and quantitative scanning densitometry to measure the content and isoform composition of contractile proteins in opossum lower esophageal sphincter (LES), to represent tonic muscle, and circular muscle of the esophageal body (EB), to represent phasic smooth muscle.
ISSN:0363-6143
1522-1563