Nitric oxide inhibits superoxide production by inflammatory polymorphonuclear leukocytes

Nitric oxide (NO-) has a complex role in the inflammatory response. In this study, we modified the levels of endogenous NO- in vivo in an acute model of inflammation and evaluated the interactions between NO- and superoxide anion (O2-) produced by polymorphonuclear leukocytes (PMNs) accumulated in t...

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Bibliographic Details
Published in:American Journal of Physiology: Cell Physiology 1998-03, Vol.43 (3), p.827-C830
Main Authors: RODENAS, J, MITJAVILA, M. T, CARBONELL, T
Format: Article
Language:English
Subjects:
Anatomy & physiology
Biological and medical sciences
Cellular biology
Fundamental and applied biological sciences. Psychology
Inflammation
Leukocytes
Molecular and cellular biology
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Summary:Nitric oxide (NO-) has a complex role in the inflammatory response. In this study, we modified the levels of endogenous NO- in vivo in an acute model of inflammation and evaluated the interactions between NO- and superoxide anion (O2-) produced by polymorphonuclear leukocytes (PMNs) accumulated in the inflamed area.
ISSN:0363-6143
1522-1563