Comparative effects of carvedilol and amiodarone on conversion and recurrence rates of persistent atril fribrillation

Pretreatment with antiarrhythmic agents could improve cardioversion and recurrence rates in patients with persistent atrial fibrillation. In a prospective controlled trial, 145 patients were randomly assigned to treatment with carvedilol, amiodarone, or placebo for 4 weeks before electrical cardiove...

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Bibliographic Details
Published in:The American journal of cardiology 2004-09, Vol.94 (5), p.659
Main Authors: Kanoupakis, Emmanuel M, Manios, Emmanuel G, Mavrakis, Hercules E, Tzerakis, Panos G
Format: Article
Language:English
Subjects:
Cardiac arrhythmia
Cardiology
Comparative analysis
Drug therapy
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Summary:Pretreatment with antiarrhythmic agents could improve cardioversion and recurrence rates in patients with persistent atrial fibrillation. In a prospective controlled trial, 145 patients were randomly assigned to treatment with carvedilol, amiodarone, or placebo for 4 weeks before electrical cardioversion. Although the 2 drugs had similar effects on cardioversion rates, amiodarone was superior in terms of sinus rhythm maintenance after conversion. [PUBLICATION ABSTRACT]
ISSN:0002-9149
1879-1913