Inactivation of Bacteria during Stimulation of Sensitizers with High-Power Nanosecond Laser Pulses

— The results of a study of photoinactivation of bacteria during stimulation of sensitizers with nanosecond laser pulses with a power density within 1–30 MW/cm 2 are presented. The irreversible damage to living cells by shock waves developed during the formation and collapse of vapor bubbles in loca...

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Bibliographic Details
Published in:Biophysics (Oxford) 2019-07, Vol.64 (4), p.576-582
Main Authors: Letuta, S. N., Letuta, U. G., Pashkevich, S. N.
Format: Article
Language:English
Subjects:
Bacteria
Biological and Medical Physics
Biophysics
Cell Biophysics
Photoinactivation
Physics
Physics and Astronomy
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Summary:— The results of a study of photoinactivation of bacteria during stimulation of sensitizers with nanosecond laser pulses with a power density within 1–30 MW/cm 2 are presented. The irreversible damage to living cells by shock waves developed during the formation and collapse of vapor bubbles in locally heated microregions of the medium is discussed. The local heating of the medium occurred due to heat release during nonradiative relaxation of high electronic states of sensitizer molecules.
ISSN:0006-3509
1555-6654
DOI:10.1134/S0006350919040092