Preparation of Polyfunctional Biaryl Derivatives by Cyclolanthanation of 2‐Bromobiaryls and Heterocyclic Analogues Using nBu2LaCl⋅4LiCl

Various aryl‐ and heteroaryl‐substituted 2‐bromobiaryls are converted to cyclometalated lanthanum intermediates by reaction with nBu2LaCl⋅4 LiCl. These resulting lanthanum heterocycles are key intermediates for the facile preparation of functionalized 2,2′‐diiodobiaryls, silafluorenes, fluoren‐9‐one...

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Bibliographic Details
Published in:Angewandte Chemie International Edition 2019-10, Vol.58 (44), p.15631-15635
Main Authors: Baosheng Wei, Zhang, Dongchao, Yi‐Hung Chen, Lei, Aiwen, Knochel, Paul
Format: Article
Language:English
Subjects:
Aromatic compounds
Fine structure
Intermediates
Lanthanum
Lithium chloride
Spectroscopy
Ultrastructure
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Summary:Various aryl‐ and heteroaryl‐substituted 2‐bromobiaryls are converted to cyclometalated lanthanum intermediates by reaction with nBu2LaCl⋅4 LiCl. These resulting lanthanum heterocycles are key intermediates for the facile preparation of functionalized 2,2′‐diiodobiaryls, silafluorenes, fluoren‐9‐ones, phenanthrenes, and their related heterocyclic analogues. X‐ray absorption fine structure (XAFS) spectroscopy was used to rationalize the proposed structures of the involved organolanthanum species.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201908046