An epidemic of sticky silicone oil at the Rotterdam Eye Hospital. Patient review and chemical analyses

Purpose To report and study the phenomenon of abnormal silicone oil adherent to the retina at the time of removal in a number of patients. Materials and methods Chart review was performed to identify possible patient or procedural factors that could predispose to sticky silicone oil formation. Gas c...

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Bibliographic Details
Published in:Graefe's archive for clinical and experimental ophthalmology 2008-06, Vol.246 (6), p.917-922
Main Authors: Veckeneer, Marc A., de Voogd, Simone, Lindstedt, Eric W., Menz, Dirk-Henning, van Meurs, Jan C.
Format: Article
Language:English
Subjects:
Adhesiveness
Case Report
Drainage - methods
Drug Interactions
Female
Fluorocarbons - chemistry
Fluorocarbons - metabolism
Gas Chromatography-Mass Spectrometry
Humans
Intraoperative Complications
Magnetic Resonance Spectroscopy
Male
Medicine
Medicine & Public Health
Middle Aged
Ophthalmology
Retina - metabolism
Retinal Detachment - surgery
Retrospective Studies
Silicone Oils - chemistry
Silicone Oils - metabolism
Vitrectomy
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Summary:Purpose To report and study the phenomenon of abnormal silicone oil adherent to the retina at the time of removal in a number of patients. Materials and methods Chart review was performed to identify possible patient or procedural factors that could predispose to sticky silicone oil formation. Gas chromatography-mass spectroscopy and nuclear magnetic resonance spectroscopy analyses were performed on sticky silicone oil samples, on perfluorocarbon liquid and on silicone oil samples straight from the vial. Results Sticky silicone oil remnants were seen on the retina in 28 out of 234 silicone oil removal procedures between January 2001 and November 2002. Forceful removal was complicated in two patients by a choroidal hemorrhage and in one patient by a retinal tear. The use of perfluoro-octane (PFO; C 8 F 18 ) rather than perfluorodecalin (C 10 F 18 ) was related to the phenomenon (P 
ISSN:0721-832X
1435-702X
DOI:10.1007/s00417-008-0768-9