IMMUNOLOGICAL ASPECTS OF THE ASSOCIATION OF PERIODONTAL MODIFICATIONS AND ORAL RISK FACTORS

[...]most of the bacterial cells are found inside the gingival sulcus, where they are inaccessible to immune response mechanisms [2]. [...]the host reaction to the bacterial challenge has limited efficiency, while the increased cytokine levels, found inside the periodontal tissues, lead to an exagge...

Full description

Saved in:
Bibliographic Details
Published in:International journal of medical dentistry 2019-07, Vol.9 (3), p.247-251
Main Authors: Rauten, Anne-Marie, Gheorghe, Dorin Nicolae, Camen, Adrian, Olteanu, Mădălina, Pitru, Allma, Toma, Vasilica, Mârţu, Silvia, Surlin, Petra
Format: Article
Language:English
Subjects:
Bacteria
Cytokines
Dental calculus
Disease
Immune response
Inflammation
Oral hygiene
Orthodontics
Periodontal diseases
Risk factors
Root resorption
Teeth
Tumor necrosis factor-TNF
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[...]most of the bacterial cells are found inside the gingival sulcus, where they are inaccessible to immune response mechanisms [2]. [...]the host reaction to the bacterial challenge has limited efficiency, while the increased cytokine levels, found inside the periodontal tissues, lead to an exaggerated immune response that can have a damaging effect on the periodontal tissues, contributing to their dissolution [3]. Different clinical responses to similar treatments can be observed (e.g., the different time of extraction spaces closure, more efficient orthopaedic correction with functional devices in some patients, as opposed to the presence of root resorption in others). [...]we consider that the orthodontic dental movement is the result of the interaction of the aforementioned cellular mechanisms with other biological variables: extrinsic - magnitude of force [6], type of dental movement [7], or intrinsic - systemic factors [8], periodontal health [9], radicular morphology [10], age [11]. The role of dental calculus in the onset of periodontal disease is explained by the fact that its rugged surface is always covered with a fresh layer of bacterial plaque, which causes periodontal inflammation [31]. [...]dental calculus can be considered a constant source of bacterial plaque, offering a favourable environment for its development. 3.CONCLUSIONS The balance of the periodontal structures can be negatively influenced by local favoring factors of periodontal disease onset, including calculus, dento-maxillary anomalies, bruxism and certain iatrogenic elements, such as inappropriate orthodontic treatments. [...]a comprehensive periodontal assessment should be carried out for the identification and management of these factors, while also considering the important immunological implications of periodontal disease.
ISSN:2066-6063
2392-8018