Acute glucocorticoid treatment increases urinary biotin excretion and serum biotin

Previous studies have demonstrated that glucocorticoids alter biotin metabolism. To extend these studies, the effect of dexamethasone on biotin pools was analyzed in rats consuming a purified diet containing a more physiological level of dietary biotin intake (0.06 mg/kg).

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Bibliographic Details
Published in:American journal of physiology: endocrinology and metabolism 2002-03, Vol.45 (3), p.E643-E649
Main Authors: RATHMAN, Sara C, LEWIS, Brandon, MCMAHON, Robert J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Drug therapy
Excretory system
Rodents
Urine
Vitamins
Online Access:Get full text
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Description
Summary:Previous studies have demonstrated that glucocorticoids alter biotin metabolism. To extend these studies, the effect of dexamethasone on biotin pools was analyzed in rats consuming a purified diet containing a more physiological level of dietary biotin intake (0.06 mg/kg).
ISSN:0193-1849
1522-1555