Increased bone turnover is associated with protein and energy metabolism in adolescents with sickle cell anemia

Contribution of bone turnover to the hypercatabolic state observed in sickle cell anemia is unknown. We examined the associaiton between markers of bone turnover and basal rates of whole body protein turnover and energy expenditure in 28 adolescents with homozygous sickle cell anemia (HbSS) and in 2...

Full description

Saved in:
Bibliographic Details
Published in:American journal of physiology: endocrinology and metabolism 2001-03, Vol.43 (3), p.E518-E527
Main Authors: BUCHOWSKI, Maciej S, DE LA FUENTE, F. Alexander, FLAKOLL, Paul J, CHEN, Kong Y, TURNER, Ernest A
Format: Article
Language:English
Subjects:
Anemias. Hemoglobinopathies
Biological and medical sciences
Bones
Diseases of red blood cells
Hematologic and hematopoietic diseases
Medical sciences
Metabolism
Proteins
Sickle cell anemia
Teenagers
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Contribution of bone turnover to the hypercatabolic state observed in sickle cell anemia is unknown. We examined the associaiton between markers of bone turnover and basal rates of whole body protein turnover and energy expenditure in 28 adolescents with homozygous sickle cell anemia (HbSS) and in 26 matched controls with normal phenotype (HbAA).
ISSN:0193-1849
1522-1555