Changes in cardiac protein kinase C activities and isozymes in streptozotocin-induced diabetes

To understand cardiac dysfunction in diabetes, the activity of protein kinase C (PKC) and protein contents of its isozymes (PKC-alpha,-P-beta,-epsilon, and -zeta) were examined in diabetic rats upon injection oi streptozotocin (65 mg/kg iv).

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Bibliographic Details
Published in:American journal of physiology: endocrinology and metabolism 1999-11, Vol.40 (5), p.E798-E804
Main Authors: XUELIANG LIU, JINGWEI WANG, TAKEDA, N, BINAGLIA, L, PANAGIA, V, DHALLA, N. S
Format: Article
Language:English
Subjects:
Associated diseases and complications
Biochemistry
Biological and medical sciences
Diabetes
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Medical sciences
Proteins
Rodents
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Description
Summary:To understand cardiac dysfunction in diabetes, the activity of protein kinase C (PKC) and protein contents of its isozymes (PKC-alpha,-P-beta,-epsilon, and -zeta) were examined in diabetic rats upon injection oi streptozotocin (65 mg/kg iv).
ISSN:0193-1849
1522-1555