Effects of dichloroacetate infusion on human skeletal muscle metabolism at the onset of exercise

This study investigated whether dichloroacetate (DCA) decreases the reliance on substrate level phosphorylation during the transition from rest to moderate- intensity exercise in humans.

Saved in:
Bibliographic Details
Published in:American journal of physiology: endocrinology and metabolism 1999-07, Vol.40 (1), p.E18-E25
Main Authors: HOWLETT, R. A, HEIGENHAUSER, G. J. F, HULTMAN, E, HOLLIDGE-HORVAT, M. G, SPRIET, L. L
Format: Article
Language:English
Subjects:
Anatomy & physiology
Biological and medical sciences
Enzymes
Exercise
Fundamental and applied biological sciences. Psychology
Metabolism
Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page E25
container_issue 1
container_start_page E18
container_title American journal of physiology: endocrinology and metabolism
container_volume 40
creator HOWLETT, R. A
HEIGENHAUSER, G. J. F
HULTMAN, E
HOLLIDGE-HORVAT, M. G
SPRIET, L. L
description This study investigated whether dichloroacetate (DCA) decreases the reliance on substrate level phosphorylation during the transition from rest to moderate- intensity exercise in humans.
format article
fullrecord <record><control><sourceid>proquest_pasca</sourceid><recordid>TN_cdi_proquest_journals_232323106</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>43999626</sourcerecordid><originalsourceid>FETCH-LOGICAL-p566-8add73c5d27d129b98d0d8d538e8d2036c9c0dfbd0f533e4f64b527b848bbe313</originalsourceid><addsrcrecordid>eNotjltLxDAQhYMouK7-hyC-FnJp2vRRlvUCC77se81lQrumTU1S0H9vFpczMBzm48y5QhsqGKuoEOIabQjteEVl3d2iu5ROhJBW1GyDPvfOgckJB4ftaAYfYlAGssqAx9mtaQwzLjOsk5px-gJfbh5PazIe8FSMDn5ME1YZ5wEKmiCfw-AHohkT3KMbp3yCh8veouPL_rh7qw4fr--750O1iKappLK25UZY1lrKOt1JS6y0gkuQlhHemM4Q67QlTnAOtWtqLVirZS21Bk75Fj3-xy4xfK-Qcn8Ka5zLx57xsyhpCvR0gVQyyruo5lKxX-I4qfjb046KtiX8D1uyXrs</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>232323106</pqid></control><display><type>article</type><title>Effects of dichloroacetate infusion on human skeletal muscle metabolism at the onset of exercise</title><source>American Physiological Society Free</source><creator>HOWLETT, R. A ; HEIGENHAUSER, G. J. F ; HULTMAN, E ; HOLLIDGE-HORVAT, M. G ; SPRIET, L. L</creator><creatorcontrib>HOWLETT, R. A ; HEIGENHAUSER, G. J. F ; HULTMAN, E ; HOLLIDGE-HORVAT, M. G ; SPRIET, L. L</creatorcontrib><description>This study investigated whether dichloroacetate (DCA) decreases the reliance on substrate level phosphorylation during the transition from rest to moderate- intensity exercise in humans.</description><identifier>ISSN: 0193-1849</identifier><identifier>EISSN: 1522-1555</identifier><identifier>CODEN: AJPMD9</identifier><language>eng</language><publisher>Bethesda, MD: American Physiological Society</publisher><subject>Anatomy &amp; physiology ; Biological and medical sciences ; Enzymes ; Exercise ; Fundamental and applied biological sciences. Psychology ; Metabolism ; Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports</subject><ispartof>American journal of physiology: endocrinology and metabolism, 1999-07, Vol.40 (1), p.E18-E25</ispartof><rights>1999 INIST-CNRS</rights><rights>Copyright American Physiological Society Jul 1999</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=1915770$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>HOWLETT, R. A</creatorcontrib><creatorcontrib>HEIGENHAUSER, G. J. F</creatorcontrib><creatorcontrib>HULTMAN, E</creatorcontrib><creatorcontrib>HOLLIDGE-HORVAT, M. G</creatorcontrib><creatorcontrib>SPRIET, L. L</creatorcontrib><title>Effects of dichloroacetate infusion on human skeletal muscle metabolism at the onset of exercise</title><title>American journal of physiology: endocrinology and metabolism</title><description>This study investigated whether dichloroacetate (DCA) decreases the reliance on substrate level phosphorylation during the transition from rest to moderate- intensity exercise in humans.</description><subject>Anatomy &amp; physiology</subject><subject>Biological and medical sciences</subject><subject>Enzymes</subject><subject>Exercise</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Metabolism</subject><subject>Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports</subject><issn>0193-1849</issn><issn>1522-1555</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><recordid>eNotjltLxDAQhYMouK7-hyC-FnJp2vRRlvUCC77se81lQrumTU1S0H9vFpczMBzm48y5QhsqGKuoEOIabQjteEVl3d2iu5ROhJBW1GyDPvfOgckJB4ftaAYfYlAGssqAx9mtaQwzLjOsk5px-gJfbh5PazIe8FSMDn5ME1YZ5wEKmiCfw-AHohkT3KMbp3yCh8veouPL_rh7qw4fr--750O1iKappLK25UZY1lrKOt1JS6y0gkuQlhHemM4Q67QlTnAOtWtqLVirZS21Bk75Fj3-xy4xfK-Qcn8Ka5zLx57xsyhpCvR0gVQyyruo5lKxX-I4qfjb046KtiX8D1uyXrs</recordid><startdate>19990701</startdate><enddate>19990701</enddate><creator>HOWLETT, R. A</creator><creator>HEIGENHAUSER, G. J. F</creator><creator>HULTMAN, E</creator><creator>HOLLIDGE-HORVAT, M. G</creator><creator>SPRIET, L. L</creator><general>American Physiological Society</general><scope>IQODW</scope><scope>7QP</scope><scope>7TS</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>19990701</creationdate><title>Effects of dichloroacetate infusion on human skeletal muscle metabolism at the onset of exercise</title><author>HOWLETT, R. A ; HEIGENHAUSER, G. J. F ; HULTMAN, E ; HOLLIDGE-HORVAT, M. G ; SPRIET, L. L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p566-8add73c5d27d129b98d0d8d538e8d2036c9c0dfbd0f533e4f64b527b848bbe313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Anatomy &amp; physiology</topic><topic>Biological and medical sciences</topic><topic>Enzymes</topic><topic>Exercise</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Metabolism</topic><topic>Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HOWLETT, R. A</creatorcontrib><creatorcontrib>HEIGENHAUSER, G. J. F</creatorcontrib><creatorcontrib>HULTMAN, E</creatorcontrib><creatorcontrib>HOLLIDGE-HORVAT, M. G</creatorcontrib><creatorcontrib>SPRIET, L. L</creatorcontrib><collection>Pascal-Francis</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Physical Education Index</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>American journal of physiology: endocrinology and metabolism</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HOWLETT, R. A</au><au>HEIGENHAUSER, G. J. F</au><au>HULTMAN, E</au><au>HOLLIDGE-HORVAT, M. G</au><au>SPRIET, L. L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of dichloroacetate infusion on human skeletal muscle metabolism at the onset of exercise</atitle><jtitle>American journal of physiology: endocrinology and metabolism</jtitle><date>1999-07-01</date><risdate>1999</risdate><volume>40</volume><issue>1</issue><spage>E18</spage><epage>E25</epage><pages>E18-E25</pages><issn>0193-1849</issn><eissn>1522-1555</eissn><coden>AJPMD9</coden><abstract>This study investigated whether dichloroacetate (DCA) decreases the reliance on substrate level phosphorylation during the transition from rest to moderate- intensity exercise in humans.</abstract><cop>Bethesda, MD</cop><pub>American Physiological Society</pub></addata></record>
fulltext fulltext
identifier ISSN: 0193-1849
ispartof American journal of physiology: endocrinology and metabolism, 1999-07, Vol.40 (1), p.E18-E25
issn 0193-1849
1522-1555
language eng
recordid cdi_proquest_journals_232323106
source American Physiological Society Free
subjects Anatomy & physiology
Biological and medical sciences
Enzymes
Exercise
Fundamental and applied biological sciences. Psychology
Metabolism
Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports
title Effects of dichloroacetate infusion on human skeletal muscle metabolism at the onset of exercise
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T12%3A48%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pasca&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20dichloroacetate%20infusion%20on%20human%20skeletal%20muscle%20metabolism%20at%20the%20onset%20of%20exercise&rft.jtitle=American%20journal%20of%20physiology:%20endocrinology%20and%20metabolism&rft.au=HOWLETT,%20R.%20A&rft.date=1999-07-01&rft.volume=40&rft.issue=1&rft.spage=E18&rft.epage=E25&rft.pages=E18-E25&rft.issn=0193-1849&rft.eissn=1522-1555&rft.coden=AJPMD9&rft_id=info:doi/&rft_dat=%3Cproquest_pasca%3E43999626%3C/proquest_pasca%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-p566-8add73c5d27d129b98d0d8d538e8d2036c9c0dfbd0f533e4f64b527b848bbe313%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=232323106&rft_id=info:pmid/&rfr_iscdi=true