Hindlimb unloading in rat decreases preosteoblast proliferation assessed in vivo with BrdU incorporation

Immobilization affects bone formation. However, the mechanisms regulating the decrease in osteoblast recruitment remain unclear. The aim of our study was to determine in vivo osteoblastic proliferation after short-term immobilization among the different bone compartments.

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Published in:American journal of physiology: endocrinology and metabolism 1998, Vol.37 (1), p.E108-E114
Main Authors: BAROU, O, PALLE, S, VICO, L, ALEXANDRE, C, LAFAGE-PROUST, M.-H
Format: Article
Language:English
Subjects:
Anatomy & physiology
Biological and medical sciences
Diseases of the osteoarticular system
Medical sciences
Osteoporosis
Vascular bone diseases
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container_end_page E114
container_issue 1
container_start_page E108
container_title American journal of physiology: endocrinology and metabolism
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creator BAROU, O
PALLE, S
VICO, L
ALEXANDRE, C
LAFAGE-PROUST, M.-H
description Immobilization affects bone formation. However, the mechanisms regulating the decrease in osteoblast recruitment remain unclear. The aim of our study was to determine in vivo osteoblastic proliferation after short-term immobilization among the different bone compartments.
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source American Physiological Society Free
subjects Anatomy & physiology
Biological and medical sciences
Diseases of the osteoarticular system
Medical sciences
Osteoporosis
Vascular bone diseases
title Hindlimb unloading in rat decreases preosteoblast proliferation assessed in vivo with BrdU incorporation
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