High-frequency oscillations in circulating amylin concentrations in healthy humans

Amylin is stored in the pancreatic beta-cell granules and cosecreted iwth insulin in response to nutrient stimuli. To gain further insight into control of hormonal release in beta-cell physiology, we examined whether amylin, like insulin, circulates in a high-frequency oscillatory pattern, and if it...

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Bibliographic Details
Published in:American journal of physiology: endocrinology and metabolism 2000-03, Vol.41 (3), p.E484-E490
Main Authors: JUHL, C. B, PØRKSEN, N, STURIS, J, HANSEN, A. P, VELDHUIS, J. D, PINCUS, S, FINEMAN, M, SCHMITZ, O
Format: Article
Language:English
Subjects:
Biological and medical sciences
Endocrine pancreas
Endocrine system
Fundamental and applied biological sciences. Psychology
Hormones
Hormones. Régulation
Insulin
Vertebrates: endocrinology
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Summary:Amylin is stored in the pancreatic beta-cell granules and cosecreted iwth insulin in response to nutrient stimuli. To gain further insight into control of hormonal release in beta-cell physiology, we examined whether amylin, like insulin, circulates in a high-frequency oscillatory pattern, and if it does, to compare the secretory patterns of the two hormones.
ISSN:0193-1849
1522-1555