Antecedent protein restriction exacerbates development of impaired insulin action after high-fat feeding

The study investigated whether a persistant impairment of insulin secretion resulting from mild protein restriction predisposes to loss of glucoregulatory control and impaired insulin action after the subsequent imposition of the diabetogenic challenge of high-fat feeding.

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Bibliographic Details
Published in:American journal of physiology: endocrinology and metabolism 1999, Vol.39 (1), p.E85-E93
Main Authors: HOLNESS, M. J, SUGDEN, M. C
Format: Article
Language:English
Subjects:
Biological and medical sciences
Diet
Endocrine system
Feeding. Feeding behavior
Fundamental and applied biological sciences. Psychology
Insulin
Oils & fats
Pancreas
Proteins
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online Access:Get full text
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Description
Summary:The study investigated whether a persistant impairment of insulin secretion resulting from mild protein restriction predisposes to loss of glucoregulatory control and impaired insulin action after the subsequent imposition of the diabetogenic challenge of high-fat feeding.
ISSN:0193-1849
1522-1555