Cortisol infusion depresses the ratio of bioactive to immunoreactive ACTH in adrenalectomized sheep fetuses

We examined the effects of exogenous cortisol on plasma immunoreactive adrenocorticotropic hormone (iACTH), bioactive ACTH (bACTH), and ACTH-(1-39) in nine adrenalectomized fetuses at 126-130 and 136-140 days of gestation.

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Bibliographic Details
Published in:American journal of physiology: endocrinology and metabolism 1998-03, Vol.37 (3), p.E391-E396
Main Authors: ZEHNDER, T. J, VALEGO, N. K, SCHWARTZ, J, GREEN, J, ROSE, J. C
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cortisone
Fetuses
Fundamental and applied biological sciences. Psychology
Hormones
Hormones and neuropeptides. Regulation
Hypothalamus. Hypophysis. Epiphysis. Urophysis
Pituitary gland
Sheep
Vertebrates: endocrinology
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Description
Summary:We examined the effects of exogenous cortisol on plasma immunoreactive adrenocorticotropic hormone (iACTH), bioactive ACTH (bACTH), and ACTH-(1-39) in nine adrenalectomized fetuses at 126-130 and 136-140 days of gestation.
ISSN:0193-1849
1522-1555