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Reduction of spontaneous and irradiation-induced apoptosis in small intestine of IGF-I transgenic mice

Insulin-like growth factor I may promote survival of putative stem cells in the small intestinal epithelium. Mitosis and apoptosis were quantified in crypts of nonirradiated and irradiated IGF-I transgenic and wild-type littermates.

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Bibliographic Details
Published in:American journal of physiology: Gastrointestinal and liver physiology 2002-08, Vol.46 (2), p.G457-G464
Main Authors: WILKINS, Heather R, OHNEDA, Kinuko, KEKU, Temitope O, D'ERCOLE, A. Joseph, FULLER, C. Randall, WILLIAMS, Kristen L, LUND, P. Kay
Format: Article
Language:English
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Summary:Insulin-like growth factor I may promote survival of putative stem cells in the small intestinal epithelium. Mitosis and apoptosis were quantified in crypts of nonirradiated and irradiated IGF-I transgenic and wild-type littermates.
ISSN:0193-1857
1522-1547