Cytochrome c release into cytosol with subsequent caspase activation during warm ischemia in rat liver

Apoptosis plays an important role in liver ischemia and reperfusion (I/R) injury. However, the molecular basis of apoptosis in I/R injury is poorly understood.

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Bibliographic Details
Published in:American journal of physiology: Gastrointestinal and liver physiology 2001-10, Vol.44 (4), p.G1115-G1123
Main Authors: SOEDA, Junpei, MIYAGAWA, Shinichi, SANO, Kenji, MASUMOTO, Junya, TANIGUCHI, Shun'Ichiro, KAWASAKI, Seiji
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cells
Deoxyribonucleic acid
DNA
Gastroenterology. Liver. Pancreas. Abdomen
Liver
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Medical sciences
Other diseases. Semiology
Rodents
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Description
Summary:Apoptosis plays an important role in liver ischemia and reperfusion (I/R) injury. However, the molecular basis of apoptosis in I/R injury is poorly understood.
ISSN:0193-1857
1522-1547