Fibrogenesis. III. Posttranscriptional regulation of type I collagen

There are several independent metabolic steps that determine the level of a protein in eukaryotic cells. the steady-state level of the mRNA encoding the specific protein is determined by rate of transcription, percentage of transcripts that are ultimately processed and transported to the cytoplasm,...

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Bibliographic Details
Published in:American journal of physiology: Gastrointestinal and liver physiology 2000-09, Vol.42 (3), p.G471-G476
Main Authors: LINDQUIST, J. N, MARZLUFF, W. F, STEFANOVIC, B
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cytokines
Gastroenterology. Liver. Pancreas. Abdomen
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Medical sciences
Metabolism
Other diseases. Semiology
Proteins
Ribonucleic acid
RNA
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Summary:There are several independent metabolic steps that determine the level of a protein in eukaryotic cells. the steady-state level of the mRNA encoding the specific protein is determined by rate of transcription, percentage of transcripts that are ultimately processed and transported to the cytoplasm, and half-life of the mRNA in cytoplasm.
ISSN:0193-1857
1522-1547