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Pancreatic phospholipase A2 from the small intestine is a secretin-releasing factor in rats

A secretin-releasing activity exists in the upper small intestine and pancreatic jucie in the rat and the dog. Group I pancreatic phospholipase A2 (PLA2) in canine pancreatic juice and porcine pancreatic PLA2 stimulate the release of secretin from both STC-1 cells and a secretin-producing cell (S ce...

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Bibliographic Details
Published in:American journal of physiology: Gastrointestinal and liver physiology 2001-08, Vol.44 (2), p.G526-G532
Main Authors: LI, James P, CHANG, Ta-Min, WAGNER, David, CHEY, William Y
Format: Article
Language:English
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Summary:A secretin-releasing activity exists in the upper small intestine and pancreatic jucie in the rat and the dog. Group I pancreatic phospholipase A2 (PLA2) in canine pancreatic juice and porcine pancreatic PLA2 stimulate the release of secretin from both STC-1 cells and a secretin-producing cell (S cell)-enriched prepartion isolated from rat duodenal mucosa.
ISSN:0193-1857
1522-1547