In vitro evidence that rabbit distal colonic muscularis mucosae has a Clostridium difficile toxin A receptor

In the rabbit ileum Clostridium difficile toxin A causes inflammation and mucosal damage via a specific glycoprotein receptor that contains alpha-D-galactose. In rabbit colon toxin A also causes inflammation, and this is associated with eicosanoid production.

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Bibliographic Details
Published in:American journal of physiology: Gastrointestinal and liver physiology 1998-09, Vol.38 (3), p.G402-G409
Main Authors: PERCY, W. H, BURAKOFF, R, ROSE, K, DESAI, H. P, POTHOULAKIS, C, EGLOW, R
Format: Article
Language:English
Subjects:
Biochemistry
Biological and medical sciences
Colon
Fundamental and applied biological sciences. Psychology
Intestine. Mesentery
Rabbits
Toxicity
Vertebrates: digestive system
Online Access:Get full text
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Description
Summary:In the rabbit ileum Clostridium difficile toxin A causes inflammation and mucosal damage via a specific glycoprotein receptor that contains alpha-D-galactose. In rabbit colon toxin A also causes inflammation, and this is associated with eicosanoid production.
ISSN:0193-1857
1522-1547