Genetic differences in cholesterol absorption in 129/Sv and C57BL/6 mice : Effect on cholesterol responsiveness

This study compared the cholesterolemic response of two strains of mice with genetically determined differences in cholesterol absorption. When fed a basal low-cholesterol diet, 129/Sv mice absorbed cholesterol twice as efficiently as did C57BL/6 mice (44% vs. 20%).

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Bibliographic Details
Published in:American journal of physiology: Gastrointestinal and liver physiology 1999-05, Vol.39 (5), p.G1117-G1124
Main Authors: JOLLEY, C. D, DIETSCHY, J. M, TURLEY, S. D
Format: Article
Language:English
Subjects:
Anatomy & physiology
Biological and medical sciences
Cholesterol
Feces
Fundamental and applied biological sciences. Psychology
Genetics
Intestine. Mesentery
Rodents
Small intestine
Vertebrates: digestive system
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Description
Summary:This study compared the cholesterolemic response of two strains of mice with genetically determined differences in cholesterol absorption. When fed a basal low-cholesterol diet, 129/Sv mice absorbed cholesterol twice as efficiently as did C57BL/6 mice (44% vs. 20%).
ISSN:0193-1857
1522-1547