Differential lobular induction in rat liver of gluthathione S-transferase A1/A2 by phenobarbital

Phenobarbital and other xenobiotics induce drug-metabolizing enzymes, including glutathione S-transferase A1/A2 (rGSTA1/A2). We examined the mechanism of induction of rGSTA1/A2 in rat livers after phenobarbital treatment.

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Bibliographic Details
Published in:American journal of physiology: Gastrointestinal and liver physiology 2000-04, Vol.41 (4), p.G542
Main Authors: Niazy Selim, Branum, Gene D, Liu, Xia, Whalen, Richard, Boyer, Thomas D
Format: Article
Language:English
Subjects:
Enzymes
Liver
Ribonucleic acid
RNA
Rodents
Online Access:Get full text
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Description
Summary:Phenobarbital and other xenobiotics induce drug-metabolizing enzymes, including glutathione S-transferase A1/A2 (rGSTA1/A2). We examined the mechanism of induction of rGSTA1/A2 in rat livers after phenobarbital treatment.
ISSN:0193-1857
1522-1547