Cell type-specific requirement of the MAPK pathway for the growth factor action of gastrin

Gastrin (G17) has a CCKB receptor-mediated growth-promoting effect on AR42J rat acinar cell line that is linked to induction of both mitogen-activated protein kinase (MAPK) and c-fos gene expression.

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Bibliographic Details
Published in:American journal of physiology: Gastrointestinal and liver physiology 1999-06, Vol.39 (6), p.G1363-G1372
Main Authors: STEPAN, V. M, DICKINSON, C. J, DEL VALLE, J, MATSUSHIMA, M, TODISCO, A
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cells
Cellular biology
Digestive system
Enzymes
Fundamental and applied biological sciences. Psychology
Genes
Hormones and neuropeptides. Regulation
Hypothalamus. Hypophysis. Epiphysis. Urophysis
Vertebrates: endocrinology
Online Access:Get full text
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Description
Summary:Gastrin (G17) has a CCKB receptor-mediated growth-promoting effect on AR42J rat acinar cell line that is linked to induction of both mitogen-activated protein kinase (MAPK) and c-fos gene expression.
ISSN:0193-1857
1522-1547