Evaluation of the clinical application of Auto-Planning module for IMRT plans of left breast cancer

Even with advanced inverse intensity modulated radiation therapy (IMRT) technique, the optimization of treatment plans remains a time-consuming task and the outcome is highly influenced by the experience of the planner and time pressure. Automated treatment planning is a current hot topic and new fr...

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Bibliographic Details
Published in:Radiation physics and chemistry (Oxford, England : 1993) England : 1993), 2020-01, Vol.166, p.108500, Article 108500
Main Authors: Liu, Fang-Yu, Dong, Zhi-Wei, Yang, Hui-Bin, Shi, Hong-Yun
Format: Article
Language:English
Subjects:
Algorithms
Auto-planning
Automation
Breast cancer
Cancer therapies
Intensity modulated radiation therapy
Left breast cancer
Lungs
Modules
Optimization
Organs
Planning
Quality assurance
Quality control
Radiation therapy
Rank tests
Standardization
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Summary:Even with advanced inverse intensity modulated radiation therapy (IMRT) technique, the optimization of treatment plans remains a time-consuming task and the outcome is highly influenced by the experience of the planner and time pressure. Automated treatment planning is a current hot topic and new frontier in radiotherapy, which is expected to minimize the above problems. The quality and efficacy of the IMRT plans generated by the Auto-Planning module of the Pinnacle3 treatment planning system (TPS) were evaluated by comparing with traditional manual plans (MPs) for left breast cancer. Dose distributions of planning target volume (PTV) and organs at risk (OARs), treatment parameters including monitor units and number of control points, the planning time, and the quality assurance (QA) results were statistically compared for two types of treatment plans by Wilcoxon matched-pair signed-rank test followed by Bonferroni correction with a corrected significance threshold of 0.2%. Dose homogeneity of the PTV was better with automated plans (APs) (p 
ISSN:0969-806X
1879-0895
DOI:10.1016/j.radphyschem.2019.108500