Comparison of conjunctival vascularity changes using optical coherence tomography angiography after trabeculectomy and phacotrabeculectomy

Purpose To compare the bleb vascularity using optical coherence tomography angiography (OCT‐A) between mitomycin‐C (MMC) augmented trabeculectomy and phacotrabeculectomy and to investigate the relationship between bleb vascularity and surgical outcomes. Methods We retrospectively reviewed data for 7...

Full description

Saved in:
Bibliographic Details
Published in:Acta ophthalmologica (Oxford, England) England), 2019-12, Vol.97 (S263), p.n/a
Main Author: Hyun Seo, Je
Format: Article
Language:English
Subjects:
Angiography
Brightness
Cataracts
Color
Glaucoma
Intraocular pressure
Medical imaging
Mitomycin C
Optical Coherence Tomography
Regression analysis
Structural analysis
Surgery
Surgical outcomes
Tomography
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose To compare the bleb vascularity using optical coherence tomography angiography (OCT‐A) between mitomycin‐C (MMC) augmented trabeculectomy and phacotrabeculectomy and to investigate the relationship between bleb vascularity and surgical outcomes. Methods We retrospectively reviewed data for 72 eyes from 72 glaucoma patients who underwent MMC augmented trabeculectomy with/without cataract surgery. Bleb area scans were obtained using OCT‐A during the preoperative period and 1, 2, 4, and 6 weeks, and 2, 4, and 6 months postoperatively. For conjunctival vascularity analysis, a semi‐automated program was used to calculate the densities of color and brightness of the selected area. Results Color and brightness densities were decreased in the trabeculectomy group during all periods, whereas it did not decrease in the phacotrabeculectomy group at 4 and 6 weeks, 2, 4, and 6 months. The color and brightness densities were significantly higher in the phacotrabeculectomy group than in the trabeculectomy group after 6 weeks and 2, 4, and 6 months. A Kaplan‐Meier survival graph showed that the intraocular pressure was not different according to surgery type, but glaucoma type. Logistic regression analysis revealed that the brightness density 1 week postoperation was correlated with reoperation. Conclusions Following trabeculectomy with MMC, The brightness density one week postoperation may be a predictive index for surgical outcomes, suggesting that a more accurate prediction could be made if evaluation of bleb structural analysis and bleb vascularity are performed simultaneously.
ISSN:1755-375X
1755-3768
DOI:10.1111/j.1755-3768.2019.5034