Quantitative analysis of ovarian cysts and tumors by using T2 star mapping

• Published in: The journal of obstetrics and gynaecology research 2020-01, Vol.46 (1), p.140-146
• Main Authors: Takahashi, Nozomi, Yoshino, Osamu, Hayashida, Emi, Nakamura, Masanobu, Hori, Masaaki, Iwahata, Shunsuke, Onda, Takashi, Unno, Nobuya, Fujii, Tomoyuki, Osuga, Yutaka
• Format: Article
• Language: English
• Subjects: Cysts; Differential diagnosis; endometrioma; endometriosis; Mapping; mucinous cystadenoma; Ovarian cancer; Quantitative analysis; Surgery; T2 star‐weighted MR imaging; Teratoma; Tumors
• ISSN: 1341-8076; 1447-0756
• DOI: 10.1111/jog.14157

Aim The aim of this study was to investigate the efficacy of T2 star (T2*) mapping in diagnosing ovarian cysts/ tumors. Methods Pelvic magnetic resonance examinations including T2*WI were performed before surgery in 35 patients. The region of interest, consisted of a 10 mm2 diameter circle, was set as much as possible inside ovarian tumors/cysts to measure T2*values, and mean T2* values were compared in ovarian cyst/tumor types, retrospectively. Diagnoses of 40 ovarian cysts/tumors were determined by pathological reports, in which 17 were endometriomas, 13 were mature cystic teratomas, 6 were mucinous cystadenomas and 4 were serous cystadenomas. Results The average T2* values of endometrioma was 56.8 ± 8.7 ms (mean ± SEM), which was significantly lower than that of mucinous cystadenoma (334.2 ± 58.5 ms, mean ± SEM) or serous cystadenoma (237.0 ± 45.4 ms, mean ± SEM). There was no difference in T2* values between endometrioma and mature cystic teratoma (64.1 ± 22.6 ms, mean ± SEM). Receiver operating characteristics curve analysis revealed that optimal cut‐off value for differential diagnosis of endometrioma and mucinous or serous cystadenoma was 149.2 ms as T2* value, which has an area under the curve of 0.95 (sensitivity = 92.4%, specificity = 78.6%). Conclusion T2* values were useful to diagnose various types of ovarian cyst/tumor.