Drug treatment of cerebral vasospasm after subarachnoid hemorrhage following aneurysms

Cerebral vasospasm (CVS) is a common and severe complication of aneurysmal subarachnoid hemorrhage (aSAH). Despite the improvement in treatment of aSAH, CVS complicating aSAH has remained the main cause of death. CVS begins most often on the third day after the ictal event and reaches the maximum on...

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Bibliographic Details
Published in:Chinese neurosurgical journal 2016-02, Vol.2 (1), p.1, Article 4
Main Authors: Liu, Yong-fei, Qiu, Han-Cheng, Su, Juan, Jiang, Wei-Jian
Format: Article
Language:English
Subjects:
Aneurysms
Blood pressure
Carotid arteries
Clinical outcomes
Clinical trials
Hemorrhage
Ischemia
Kinases
Proteins
Signal transduction
Smooth muscle
Veins & arteries
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Summary:Cerebral vasospasm (CVS) is a common and severe complication of aneurysmal subarachnoid hemorrhage (aSAH). Despite the improvement in treatment of aSAH, CVS complicating aSAH has remained the main cause of death. CVS begins most often on the third day after the ictal event and reaches the maximum on the 5th–7th postictal days. Several therapeutic modalities have been employed to prevent or reverse CVS. The aim of this review is to summate all the available drug treatment modalities for vasospasm.
ISSN:2057-4967
2057-4967
DOI:10.1186/s41016-016-0023-x