Novel derivatives of 3,5-di-tert-butylpyrocatechol with pharmacophore substituents

New potentially bioactive derivatives comprising spatially hindered pyrocatechol linked to hydrazine, acid hydrazides (including isoniazid), and acetylcysteine by a covalent bridge, have been obtained. The structure of the obtained compounds was studied by X-ray diffraction analysis.

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Bibliographic Details
Published in:Russian chemical bulletin 2019-12, Vol.68 (12), p.2290-2297
Main Authors: Ukhin, L. Yu, Kuz´mina, L. G., Alexeenko, D. V., Belousova, L. V., Morkovnik, A. S., Shepelenko, E. N., Podshibyakin, V. A., Borodkin, G. S., Dmitrieva, O. I.
Format: Article
Language:English
Subjects:
Bridges
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Derivatives
Full Articles
Hydrazides
Hydrazines
Inorganic Chemistry
Organic Chemistry
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Description
Summary:New potentially bioactive derivatives comprising spatially hindered pyrocatechol linked to hydrazine, acid hydrazides (including isoniazid), and acetylcysteine by a covalent bridge, have been obtained. The structure of the obtained compounds was studied by X-ray diffraction analysis.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-019-2702-1