Perceptions among the U.S. population of value of Japanese encephalitis (JE) vaccination for travel to JE-endemic countries

Japanese encephalitis (JE) is a rare but potentially severe disease among travelers. JE vaccine in the United States costs $500–$600 for a 2-dose series and is safe and effective but rare serious adverse events can occur. Our survey investigated likelihood of vaccine receipt for travel. An electroni...

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Bibliographic Details
Published in:Vaccine 2020-02, Vol.38 (9), p.2117-2121
Main Authors: Hills, Susan L., Fischer, Marc, Biggerstaff, Brad J.
Format: Article
Language:English
Subjects:
Adult
Decision making
Education
Encephalitis
Encephalitis, Japanese - epidemiology
Encephalitis, Japanese - prevention & control
Ethnicity
Family income
Generalized linear models
Health risks
Heterogeneity
Households
Humans
Immunization
Japanese encephalitis
Japanese Encephalitis Vaccines - administration & dosage
Japanese Encephalitis Vaccines - adverse effects
Polls & surveys
Population statistics
Risk perception
Side effects
Surveys and Questionnaires
Travel
Trends
United States - epidemiology
Vaccination
Vaccination - psychology
Vaccination - statistics & numerical data
Vaccine
Vaccines
Variables
Vector-borne diseases
Citations: Items that this one cites
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Description
Summary:Japanese encephalitis (JE) is a rare but potentially severe disease among travelers. JE vaccine in the United States costs $500–$600 for a 2-dose series and is safe and effective but rare serious adverse events can occur. Our survey investigated likelihood of vaccine receipt for travel. An electronically-administered survey was conducted among U.S. adults. Participants were presented a hypothetical scenario on travel to a JE-endemic country and JE vaccine characteristics and responded on likelihood of vaccination. Overall, 6384 (59%) of 10,904 persons completed the questions. Population estimates indicated 32% would be likely and 42% were unlikely to be vaccinated, and 26% were unsure. Among those likely to get vaccinated, important factors were disease risk and severity, and vaccine safety. Among those unlikely, cost, disease risk, and possibility of serious side effects ranked highest. There is population heterogeneity in perception of JE disease risk and value of vaccination.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2020.01.048