Seizures Associated With Leucovorin Administration in Cancer Patients

Cases providing support for the hypothesis that folinic acid administration can precipitate seizures in cancer patients are presented. An association between high-dose leucovorin and seizures in cancer patients was found.

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Bibliographic Details
Published in:JNCI : Journal of the National Cancer Institute 1995-01, Vol.87 (1), p.56-58
Main Authors: MEROPOL, NEAL J., CREAVEN, PATRICK J., PETRELLI, NICHOLAS J., WHITE, ROBERT M., ARBUCK, SUSAN G.
Format: Article
Language:English
Subjects:
Adult
Aged
Cancer
Convulsions
Drug therapy
Humans
Leucovorin - adverse effects
Leucovorin - therapeutic use
Medical research
Middle Aged
Neoplasms - drug therapy
Seizures - chemically induced
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Description
Summary:Cases providing support for the hypothesis that folinic acid administration can precipitate seizures in cancer patients are presented. An association between high-dose leucovorin and seizures in cancer patients was found.
ISSN:0027-8874
1460-2105
DOI:10.1093/jnci/87.1.56