PERIODONTAL CHANGES AND THE NON-ALCOHOLIC FATTY LIVER DISEASE

• Published in: International journal of medical dentistry 2018-07, Vol.8 (3), p.280-287
• Main Authors: Arsenie, Cristian, Săndulescu, Daniela-Larisa, Popescu, Dora Maria, Gheorghe, Dorin Nicolae, Mârţu, Alexandra, Foia, Liliana, Şurlin, Petra, Rogoveanu, Ion
• Format: Article
• Language: English
• Subjects: Adipocytes; Alcohol; Biofilms; Cardiovascular disease; Coronary artery disease; Diabetes; Diabetes mellitus (non-insulin dependent); Disease resistance; Fatty liver; Heart diseases; Homeostasis; Immune response; Immune system; Inflammation; Insulin; Insulin resistance; Ischemia; Kinases; Liver cancer; Liver diseases; Metabolic disorders; Metabolism; Mutation; Obesity; Pathology; Periodontal diseases; Periodontitis; Risk factors; Teeth
• ISSN: 2066-6063; 2392-8018

In periodontal medicine, such metabolic disorders are viewed as high risk factors for the onset of periodontal disease, considering their impact on the host immune response. Keywords: periodontal disease, non-alcoholic fatty liver disease, insulin resistance, diabetes mellitus. 1.INTRODUCTION The liver, a crucial organ for the keeping of the general homeostasis and well-being, is the prime location where all the elements and particles that are introduced into the body via food, drink or medicines are being transformed and metabolized. Other studies have concluded that non-alcoholic fatty liver disease increases the risk of ischemic stroke, nonf atal coronary heart disease and cardiovascular death in most type 2 diabetes mellitus [27]. Periodontitis is caused by oral pathogenic bacteria present in the dental subgingival biofilm, inducing chronic inflammation in the supporting structures of the teeth, which can lead to the formation of pockets, clinical attachment loss, and eventually tooth loss [45].