Deformation analysis of the spongious sample in simulated physiological conditions based on in-situ compression, 4D computed tomography and fast readout detector

• Published in: Journal of instrumentation 2018-11, Vol.13 (11), p.C11021-C11021, Article C11021
• Main Authors: Fíla, T., Šleichrt, J., Kytýř, D., Kumpová, I., Vopálenský, M., Zlámal, P., Rada, V., Vavřík, D., Koudelka, P., Senck, S.
• Format: Article
• Language: English
• Subjects: Algorithms; Bioreactors; Computed tomography; Computer simulation; Deformation analysis; Digital imaging; Flat panels; Image acquisition; Metal oxides; Modular equipment; Physiology; Sensors; Slip rings; Tomography; Volumetric analysis; Volumetric strain
• ISSN: 1748-0221; 1748-0221
• DOI: 10.1088/1748-0221/13/11/C11021

In this work, an in-house designed table top loading device equipped with a bioreactor is used for the in-situ compression of a spongious sample in simulated physiological conditions. On-the-fly 4D computed tomography is used as a tool for the advanced volumetric analysis of the deforming microstructure of the specimen. The loading device with the bioreactor was placed directly onto the rotational stage of a modular X-ray scanner. As the loading device is equipped with a slip-ring cable system, it can perform an unlimited number of revolutions during the on-the-fly scanning procedure. A complementary metal-oxide-semiconductor flat panel detector with a fast readout was used for the acquisition of the X-ray images. The specimen was compressed with a low loading velocity. A set of the volumetric data capturing the deformation of the specimen during the experiment was prepared from the images acquired by the detector. A digital volume correlation algorithm was used for the evaluation of the volumetric strain fields in the specimen.