A Rh(iii)-catalyzed regioselective intermolecular oxa-Pauson–Khand reaction of alkynes, arylboronic acids and CO to form butenolides

A Rh(iii)-catalyzed regioselective intermolecular oxa-Pauson–Khand reaction of arylboronic acids, alkynes and CO for the synthesis of butenolides has been developed. The multi-step reaction proceeded smoothly in the presence of [RhCp*Cl2]2 catalyst, NaOAc base and CH3OH additive. The reaction used r...

Full description

Saved in:
Bibliographic Details
Published in:Organic chemistry frontiers an international journal of organic chemistry 2020-03, Vol.7 (5), p.763-767
Main Authors: Mi-Na, Zhao, Zhang, Ying, Ge, Ning, Le, Yu, Wang, Shun, Zhi-Hui Ren, Zheng-Hui, Guan
Format: Article
Language:English
Subjects:
Acids
Alkynes
Catalysts
Functional groups
NMR
Nuclear magnetic resonance
Organic chemistry
Regioselectivity
Rhodium
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A Rh(iii)-catalyzed regioselective intermolecular oxa-Pauson–Khand reaction of arylboronic acids, alkynes and CO for the synthesis of butenolides has been developed. The multi-step reaction proceeded smoothly in the presence of [RhCp*Cl2]2 catalyst, NaOAc base and CH3OH additive. The reaction used readily available starting materials, tolerated various functional groups, and afforded valuable butenolides in good yields with high regioselectivity.
ISSN:2052-4110
2052-4110
DOI:10.1039/c9qo01486a