Synthesis of a conductive polymer thin film having a choline phosphate side group and its bioadhesive properties

A conductive polymer thin film having choline phosphate as the side group was prepared. Quartz crystal microbalance (QCM) was employed to evaluate the adsorption of the model protein, bovine serum albumin (BSA), on the films deposited on indium tin oxide (ITO) electrodes. Cell adsorption on the film...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2020-03, Vol.56 (18), p.2691-2694
Main Authors: Mukai, Masaru, Cheng, Chao-Hung, Ma, Wei, Chin, Mi, Lin, Chia-Hsin, Luo, Shyh-Chyang, Takahara, Atsushi
Format: Article
Language:English
Subjects:
Adsorption
Animals
Cattle
Chemical synthesis
Choline
Conducting polymers
Contact angle
Electric Conductivity
Electrodes
Indium tin oxides
Mice
Microbalances
Molecular Structure
NIH 3T3 Cells
NMR
Nuclear magnetic resonance
Optical Imaging
Phosphorylcholine - chemistry
Polymer films
Polymers - chemical synthesis
Polymers - chemistry
Quartz Crystal Microbalance Techniques
Quartz crystals
Serum albumin
Serum Albumin, Bovine - chemistry
Surface Properties
Thin films
Tin Compounds - chemistry
X ray photoelectron spectroscopy
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Summary:A conductive polymer thin film having choline phosphate as the side group was prepared. Quartz crystal microbalance (QCM) was employed to evaluate the adsorption of the model protein, bovine serum albumin (BSA), on the films deposited on indium tin oxide (ITO) electrodes. Cell adsorption on the film was evaluated by a fibroblast NIH3T3. A conductive polymer thin film having choline phosphate as the side group was prepared. The polymer thin film can prevent bovine serum albumin binding while present nice fibroblast cell adhesion.
ISSN:1359-7345
1364-548X
DOI:10.1039/c9cc09949b