Zeolite anchored Zr-ZSM-5 as an eco-friendly, green, and reusable catalyst in Hantzsch synthesis of dihydropyridine derivatives

• Published in: Materials chemistry and physics 2020-02, Vol.242, p.122497, Article 122497
• Main Authors: Kusampally, Uppalaiah, Dhachapally, Naresh, Kola, Ramesh, Kamatala, Chinna Rajanna
• Format: Article
• Language: English
• Subjects: Acetoacetanilides; Aldehydes; Ammonium hydroxide; Catalysts; Catalytic activity; Chemical synthesis; Combinatorial analysis; Conventional and microwave-synthesis; Derivatives; Ethanol; Metal switch over Zr-ZSM-5catalyst; Micro and nanostructure solid surface; Multi-component reactions (MCR); NMR; Nuclear magnetic resonance; Reaction time; Reusable components; Shorter reaction times and high product yields; Zeolites; Zirconium
• ISSN: 0254-0584; 1879-3312
• DOI: 10.1016/j.matchemphys.2019.122497

In this study, the authors have developed a simple and eco-friendly metal switch over Zeo-catalyst Zr-ZSM-5. It is an efficient and novel reusable heterogeneous solid catalyst for one pot multi component synthesis of triphenyl pyridine- 3, 5-dicarboxamide, and 2,6-dimethyl-1,4- dihydropyridine-3,5-dicarboxylate from Acetoacetanilide/ethyl acetoacetate, ACOONH4/NH4OH and various Aromatic Aldehydes. Reactions afforded very good product yields (87–95%) in a short reaction time (27–35 min) in ethanol at an appropriate temperature. Prepared catalyst was comfortably recycled for four to five times (4–5 runs) without significant loss of catalytic activity. Zr-ZSM-5 is also used as a green catalyst for the combinatorial syntheses of dihydropyridine. The solid catalyst was characterized by XRD, SEM/EDS and BET SA-PSD, and the resulting substituted dihydropyridine derivatives were characterized and confirmed by 1H and 13C NMR, IR, and elemental spectral data. To create your abstract, type over the instructions in the template box below.Fonts or abstract dimensions should not be changed or altered. [Display omitted] •Zeolite anchored Zr-ZSM-5 is developed as an eco-friendly, green and reusable catalyst.•Developed catalyst worked efficiently in Hantzsch synthesis of dihydropyridine derivatives.•Microwave assisted reactions reduced reaction times and increased product yields.•Zeolite anchored Zr-ZSM-5 could be recycled efficiently in 4–5 runs.