Role of Nano-formulation in the treatment of Onychomycosis

[...]the diagnosis of the disease is delayed which results in less chances for the cure of the disease. The enzyme is studied to be having higher activity at alkaline pH (7 - 10) and temperature is said to be in the range of 40°C - 60°C. The enzyme finds its use widely in hydrolyzing the proteins su...

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Bibliographic Details
Published in:Research journal of pharmacy and technology 2020, Vol.13 (1), p.453-455
Main Authors: Srinidhi, K R, Subrahmanyam, V M, Alex, Angel Treasa, Mathew, A Jesil, Kamath, B Venkatesh
Format: Article
Language:English
Subjects:
Acne
Bioremediation
Chemical bonds
Disease
Enzymes
Fungi
Hair
Infections
Keratin
Peptides
Proteins
Sulfur content
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Summary:[...]the diagnosis of the disease is delayed which results in less chances for the cure of the disease. The enzyme is studied to be having higher activity at alkaline pH (7 - 10) and temperature is said to be in the range of 40°C - 60°C. The enzyme finds its use widely in hydrolyzing the proteins such as hair and feathers which in turn helps the process of sewage treatment as well as in food and leather industries, feed processing for animals. [...]they find applications in bioremediation, processing of organic fertilizers, films, coatings, glue, in degradation of prion proteins, eliminating keratin in acne, and also as drug permeation enhancer (Onychomycosis). [...]to treat the infection, the drug initially has to penetrate through the nail plate which is difficult as the nail plate is made up of the protein hard keratin.
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.5958/0974-360X.2020.00088.8