Analysis of Chemical Constituents and Antiparasitic Activities of the Extracts of Imperata cylindrica

• Published in: Research journal of pharmacy and technology 2020-02, Vol.13 (2), p.653-658
• Main Authors: Lalthanpuii, P. B., Zarzokimi, Lalchhandama, K.
• Format: Article
• Language: English
• Subjects: Acids; Chromatography; Infections; Parasites; Tropical diseases
• ISSN: 0974-3618; 0974-360X; 0974-306X
• DOI: 10.5958/0974-360X.2020.00125.0

The underground part is most commonly used and is applied as antibacterial, anticoagulant (styptic), antipyretic (febrifuge), diuretic, skin softening (emollient), salivating (sialagogue), and soothing (tonic) agent.1 The roots are particularly effective for the treatment of jaundice, peripheral oedema, and various blood disorders including haematuria (blood urine), haematemesis (blood vomit), and nosebleed (epistaxis). There are only two reports on the bioactive compounds isolated from the leaves, which hare demonstrated to have protective effect on the nervous system,2 and blood-flow (vasodilative) regulating effects in experimental animals.3 The Mizo people of northeast India have several indigenous applications of the plant. The methanol extract of I. cylindra was analysed for chemical identification using gas chromatography-mass spectrometry system (Thermo Scientific TRACE™ 1300 ISQ™ LT). Temperature of the injector port was set at 250°C. The oven temperature was initially set at 70°C for 2 minutes and gradually raised at an increment of 10°C up to 250°C. As a carrier gas, helium was released into the oven chamber at a constant flow rate of 1 mL/min.