Diagnosis and management of iron deficiency in children with or without anemia: consensus recommendations of the SPOG Pediatric Hematology Working Group

Iron deficiency is the most prevalent nutritional deficiency affecting children and adolescents worldwide. A consistent body of epidemiological data demonstrates an increased incidence of iron deficiency at three timepoints: in the neonatal period, in preschool children, and in adolescents, where it...

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Bibliographic Details
Published in:European journal of pediatrics 2020-04, Vol.179 (4), p.527-545
Main Authors: Mattiello, Veneranda, Schmugge, Markus, Hengartner, Heinz, von der Weid, Nicolas, Renella, Raffaele
Format: Article
Language:English
Subjects:
Administration, Intravenous - adverse effects
Administration, Oral
Adolescent
Adolescents
Anemia
Anemia, Iron-Deficiency - blood
Anemia, Iron-Deficiency - diagnosis
Anemia, Iron-Deficiency - physiopathology
Anemia, Iron-Deficiency - therapy
Child
Child, Preschool
Children
Consensus
Diagnosis
Epidemiology
Ferric Compounds - administration & dosage
Ferric Compounds - adverse effects
Ferric Compounds - economics
Ferritins - blood
Humans
Infant
Infant, Newborn
Intravenous administration
Iron
Iron - blood
Iron - deficiency
Iron, Dietary - standards
Medical diagnosis
Medicine
Medicine & Public Health
Neonates
Nutrient deficiency
Pediatrics
Pediatrics - methods
Review
Switzerland
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Description
Summary:Iron deficiency is the most prevalent nutritional deficiency affecting children and adolescents worldwide. A consistent body of epidemiological data demonstrates an increased incidence of iron deficiency at three timepoints: in the neonatal period, in preschool children, and in adolescents, where it particularly affects females. Conclusion : This narrative review focuses on the most suggestive symptoms of iron deficiency in childhood, describes the diagnostic procedures in situations with or without anemia, and provides Swiss expert-based management recommendations for the pediatric context. What is Known: • Iron deficiency (ID) is one of the most common challenges faced by pediatricians. • Significant progress in the diagnosis and therapy of ID has been made over the last decade. What is New: • Our expert panel provides ID management recommendations based on the best available evidence. • They include strategies for ID diagnosis and therapy, both oral and intravenous.
ISSN:0340-6199
1432-1076
DOI:10.1007/s00431-020-03597-5