THE EFFECT OF ALLOPURINOL THERAPY ON BLOOD PRESSURE IN PATIENTS OF CHRONIC KIDNEY DISEASE WITH HYPERTENSION AND HYPERURICEMIA UNDERGOING HEMODIALYSIS

ABSTRACT Objective: To determine the effect of allopurinol therapy on blood pressure in patients of Chronic Kidney Disease with hypertension and hyperuricemia undergoing hemodialysis. Study Design: Quasi experimental study. Place and Duration of Study: Department of Medicine, Pak Emirates Military H...

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Bibliographic Details
Published in:Pakistan Armed Forces medical journal 2020-02 (1), p.S113
Main Authors: Kanza Khalid, Saeed Bin Ayaz, Anjum, Naveed, Yaseen, Laila
Format: Article
Language:English
Subjects:
Age
Allopurinol
Blood pressure
Care and treatment
Chronic kidney failure
Development and progression
Diabetes
Diabetes mellitus
Diseases
Etiology (Medicine)
Gender
Glomerulonephritis
Hemodialysis
Hypertension
Hyperuricemia
Kidney diseases
Lupus
Males
Nitric oxide
Polycystic kidney disease
Population
Type 2 diabetes
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Summary:ABSTRACT Objective: To determine the effect of allopurinol therapy on blood pressure in patients of Chronic Kidney Disease with hypertension and hyperuricemia undergoing hemodialysis. Study Design: Quasi experimental study. Place and Duration of Study: Department of Medicine, Pak Emirates Military Hospital Rawalpindi, from Nov 2015 to May 2016. Methodology: One hundred and seventy-two patients with the diagnosis of chronic kidney disease and on regular hemodialysis were selected after fulfilling the inclusion and exclusion criteria. The blood pressure of patient before and after dialysis was measured. The patients were given 100mg of allopurinol daily for three months. The blood pressure was checked weekly by the researcher before and after dialysis. The mean systolic and diastolic blood pressure before and after three months' treatment were compared using paired-sample t-tests. The efficacy was defined as attainment of blood pressure
ISSN:0030-9648
2411-8842