Synthesis and study antimicrobial activity of polybarbiturate contain triazole ring

A series of Polybarbiturate containing triazole ring were prepared via the click reaction of diazido barbiturate and dipropargyl barbiturate in the presence of CuCl and Sodium ascorbate. The structures all prepared polymers were identified by using NMR and IR techniques. In aprotic polar solvents su...

Full description

Saved in:
Bibliographic Details
Main Authors: Abbas, Hayder Kadhim, Obaid, Ehab Kareem, Salman, Farked Wahoodi, Shaheed, Hayder Ahmed, Radhi, Ali Jabbar
Format: Conference Proceeding
Language:English
Subjects:
Antiinfectives and antibacterials
Antimicrobial agents
Bacteria
Chemical reactions
Differential scanning calorimetry
Drugs
Gravimetric analysis
Low temperature
NMR
Nuclear magnetic resonance
Polymers
Stability analysis
Thermal stability
Triazoles
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A series of Polybarbiturate containing triazole ring were prepared via the click reaction of diazido barbiturate and dipropargyl barbiturate in the presence of CuCl and Sodium ascorbate. The structures all prepared polymers were identified by using NMR and IR techniques. In aprotic polar solvents such as DMF and DMSO the end products showed that polymers have high solubility at low temperatures. Thermal stability of the all polymers were determined using thermo gravimetric analysis (TGA) and differential scanning calorimetry (DSC) which indicated that they have high Tg (124–175 °C) and good thermal stability under N2 atmosphere. The synthesized polymers were evaluated antimicrobial activity against different types strains of Gram-negative and positive bacteria and showed good significant against these bacteria.
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0000240