5PSQ-002 Hypomagnesaemia alert! Monitor closely proton pump inhibitors for chronic treatment in elderly patients

Background and importanceThere have only been 175 cases of hypomagnesaemia associated with prolonged use of proton pump inhibitors (PPIs) reported to FEDRA (Spanish Pharmacovigilance, Adverse Reaction Data) since commercialisation of PPIs, despite the alert published by AEMPS in 2011.Aim and objecti...

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Bibliographic Details
Published in:European journal of hospital pharmacy. Science and practice 2020-03, Vol.27 (Suppl 1), p.A150-A150
Main Authors: Dominguez Barahona, A, Gonzalez Suarez, S, Martinez Camacho, M, Rodriguez Jimenez, E, Alonso Seco, M, Santos Azorín, A, López Álvarez, R, Toledo Davia, MA, García Marco, D
Format: Article
Language:English
Subjects:
Diuretics
Electrolytes
Geriatrics
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Summary:Background and importanceThere have only been 175 cases of hypomagnesaemia associated with prolonged use of proton pump inhibitors (PPIs) reported to FEDRA (Spanish Pharmacovigilance, Adverse Reaction Data) since commercialisation of PPIs, despite the alert published by AEMPS in 2011.Aim and objectivesTo detect hypomagnesaemia in patients admitted to an acute geriatric hospital and look for a relationship with chronic PPI treatment, and to determine the frequency of this adverse effect with respect to all hospitalised patients and the electrolyte alterations that may be related.Material and methodsA retrospective study was conducted during the first half of 2019 in admitted patients treated with magnesium in an acute geriatric 160 bed hospital. Demographic data were collected (age, sex). Hypomagnesaemia (
ISSN:2047-9956
2047-9964
DOI:10.1136/ejhpharm-2020-eahpconf.319