Rapid SARS-CoV-2 whole genome sequencing for informed public health decision making in the Netherlands

SARS-CoV-2 is a novel coronavirus that has rapidly spread across the globe. In the Netherlands, the first case of SARS-CoV-2 has been notified on the 27th of February. Here, we describe the first three weeks of the SARS-CoV-2 outbreak in the Netherlands, which started with several different introduc...

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Bibliographic Details
Published in:bioRxiv 2020-04
Main Authors: Bas B Oude Munnink, Nieuwenhuijse, David F, Stein, Mart, O'toole, Aine, Haverkarte, Manon, Mollers, Madelief, Kamga, Sandra K, Schapendonk, Claudia, Lexmond, Pascal, Pronk, Mark, Van Der Linden, Anne, Bestebroer, Theo, Chestakova, Irina, Overmars, Ronald J, Stefan Van Nieuwkoop, Molenkamp, Richard, Annemieke Van Der Eijck, Geurtsvankessel, Corine, Vennema, Harry, Meijer, Adam, Rambaut, Andrew, Jaap Van Dissel, Sikkema, Reina, Timen, Aura, Koopmans, Marion
Format: Article
Language:English
Subjects:
Coronaviruses
Decision making
Epidemiology
Genomes
Genomics
Public health
Severe acute respiratory syndrome coronavirus 2
Whole genome sequencing
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Summary:SARS-CoV-2 is a novel coronavirus that has rapidly spread across the globe. In the Netherlands, the first case of SARS-CoV-2 has been notified on the 27th of February. Here, we describe the first three weeks of the SARS-CoV-2 outbreak in the Netherlands, which started with several different introductory events from Italy, Austria, Germany and France followed by local amplification in, and later also, outside the South of the Netherlands. The timely generation of whole genome sequences combined with epidemiological investigations facilitated early decision making in an attempt to control local transmission of SARS-CoV-2 in the Netherlands. Competing Interest Statement The authors have declared no competing interest.
ISSN:2692-8205
DOI:10.1101/2020.04.21.050633