Coronavirus Disease 19 Infection Does Not Result in Acute Kidney Injury: An Analysis of 116 Hospitalized Patients from Wuhan, China

Background: Whether the patients with coronavirus disease 19 (COVID-19) infected by severe acute respiratory syndrome (SARS)-CoV-2 would commonly develop acute kidney injury (AKI) is an important issue worthy of clinical attention. This study aimed to explore the effects of SARS-CoV-2 infection on r...

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Bibliographic Details
Published in:American Journal of Nephrology 2020-05, Vol.51 (5), p.343-348
Main Authors: Wang, Luwen, Li, Xun, Chen, Hui, Yan, Shaonan, Li, Dong, Li, Yan, Gong, Zuojiong
Format: Article
Language:English
Subjects:
Acute Disease
Acute renal failure
Adult
Aged
Aged, 80 and over
Betacoronavirus
China - epidemiology
Coronavirus Infections - mortality
COVID-19
Demographic aspects
Female
Hospitalization
Humans
Kidney Diseases
Kidney Function Tests
Male
Middle Aged
Pandemics
Patient-Oriented, Translational Research
Patient-Oriented, Translational Research: Research Article
Pneumonia, Viral - mortality
Risk factors
SARS-CoV-2
Young Adult
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Summary:Background: Whether the patients with coronavirus disease 19 (COVID-19) infected by severe acute respiratory syndrome (SARS)-CoV-2 would commonly develop acute kidney injury (AKI) is an important issue worthy of clinical attention. This study aimed to explore the effects of SARS-CoV-2 infection on renal function through analyzing the clinical data of 116 hospitalized COVID-19-confirmed patients. Methods: One hundred sixteen COVID-19-confirmed patients enrolled in this study were hospitalized in the Department of Infectious Diseases, Renmin Hospital of Wuhan University from January 14 to February 13, 2020. The recorded information includes demographic data, medical history, contact history, potential comorbidities, symptoms, signs, laboratory test results, chest computer tomography scans, and treatment measures. SARS-CoV-2 RNA in 53 urine sediments of enrolled patients was detected by real-time reverse transcription-polymerase chain reaction. Results: Twelve (10.8%) patients showed mild increase of blood urea nitrogen or creatinine (
ISSN:0250-8095
1421-9670
DOI:10.1159/000507471