Human Coronavirus Infection among Children with Acute Lower Respiratory Tract Infection in Thailand

Objective: This study was performed to further identify the previously uncharacterized human coronavirus 229E (hCoV-229E) and human coronavirus OC43 (hCoV-OC43) in Thailand by using the RT-PCR technique. In addition, we performed this study in order to delineate the prevalence, the potential clinica...

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Bibliographic Details
Published in:Intervirology 2007-01, Vol.50 (2), p.71-77
Main Authors: Theamboonlers, Apiradee, Samransamruajkit, Rujipat, Thongme, Chittima, Amonsin, Alongkorn, Chongsrisawat, Voranush, Poovorawan, Yong
Format: Article
Language:English
Subjects:
Adolescent
Child
Child, Preschool
Coronavirus 229E, Human - isolation & purification
Coronavirus Infections - epidemiology
Coronavirus Infections - physiopathology
Coronavirus Infections - virology
Coronavirus OC43, Human - isolation & purification
Female
Human coronavirus 229e
Human coronavirus oc43
Humans
Infant
Infant, Newborn
Male
Molecular Sequence Data
Nasopharynx - virology
Original Paper
Phylogeny
Pneumonia, Viral - epidemiology
Pneumonia, Viral - virology
Prevalence
Respiratory Tract Infections - epidemiology
Respiratory Tract Infections - virology
Reverse Transcriptase Polymerase Chain Reaction
RNA, Viral - analysis
RNA, Viral - genetics
Sequence Analysis, DNA
Thailand - epidemiology
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Summary:Objective: This study was performed to further identify the previously uncharacterized human coronavirus 229E (hCoV-229E) and human coronavirus OC43 (hCoV-OC43) in Thailand by using the RT-PCR technique. In addition, we performed this study in order to delineate the prevalence, the potential clinical impacts and evaluation of the genetic characterization of this pathogen in young children who presented with acute lower respiratory tract infections (ALRI). Methods: We obtained nasopharyngeal secretions (NPs) from 226 children
ISSN:0300-5526
1423-0100
DOI:10.1159/000097392