The use of corticosteroids does not influence CD4+ lymphocyte recovery in HIV-infected patients with advanced immunodeficiency

Corticosteroids inhibit HIV-related immune activation and seem to have a mild favorable effect on immunological recovery in patients with CD4 + counts ≥200 cells/mm 3 . Data in patients with advanced immunodeficiency are lacking. We analyzed whether corticosteroids negatively influence the short-ter...

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Bibliographic Details
Published in:AIDS care 2020-06, Vol.32 (6), p.701-704
Main Authors: van Welzen, Berend J., de Vries, Tamar I., Arends, Joop E., Mudrikova, Tania, Hoepelman, Andy I. M.
Format: Article
Language:English
Subjects:
Adrenal Cortex Hormones - therapeutic use
AIDS/HIV
Anti-HIV Agents - therapeutic use
Antiretroviral agents
Antiretroviral drugs
Antiretroviral therapy
CD4 antigen
CD4 Lymphocyte Count
CD4-Positive T-Lymphocytes
Combination therapy
Corticoids
Corticosteroids
Drug therapy
HIV
HIV Infections - complications
HIV Infections - drug therapy
HIV
Corticosteroids
Pneumocystis
Immune recovery
Human immunodeficiency virus
Humans
Immune response
Immunodeficiency
Immunology
Lymphocytes
Pneumonia
Recovery
Recovery (Medical)
Retrospective Studies
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Summary:Corticosteroids inhibit HIV-related immune activation and seem to have a mild favorable effect on immunological recovery in patients with CD4 + counts ≥200 cells/mm 3 . Data in patients with advanced immunodeficiency are lacking. We analyzed whether corticosteroids negatively influence the short-term CD4 + lymphocyte recovery in patients with CD4 + cell counts
ISSN:0954-0121
1360-0451
DOI:10.1080/09540121.2019.1623376