Successful management of solitary gastric plasmacytoma in a 22-year-old woman using a new protocol for combination therapy

{Figure 1} Whole-body positron emission tomography (PET) scan showed fluorodeoxyglucose avid focal thickening in gastric corpus, focal colonic hypermetabolism, and diffuse marrow uptake. Considering the younger age of the patient, localized tumor, no regional lymphadenopathy, and uninvolved bone mar...

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Bibliographic Details
Published in:Journal of cancer research and therapeutics 2020-01, Vol.16 (1), p.192-193
Main Authors: Mitra, Subhashis, Chakraborty, Sulagna, Chatterjee, Prasenjit, Bhattacharyya, Maitreyee
Format: Article
Language:English
Subjects:
Anemia
Biopsy
Blood proteins
Bone marrow
Cancer treatment
Chemotherapy
Combination therapy
Endoscopy
Fever
Gastrointestinal system
Lymphomas
Medical prognosis
Multiple myeloma
Plasma
Plasmacytoma
Proteins
Radiation therapy
Radiotherapy
Surgery
Tumors
Weight loss
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Summary:{Figure 1} Whole-body positron emission tomography (PET) scan showed fluorodeoxyglucose avid focal thickening in gastric corpus, focal colonic hypermetabolism, and diffuse marrow uptake. Considering the younger age of the patient, localized tumor, no regional lymphadenopathy, and uninvolved bone marrow; EMR was deemed adequate, and further treatment was based on the combination of intravenous bortezomib, oral dexamethasone, and regional radiotherapy localized to the stomach and perigastric lymph nodes. [5] A combination protocol of EMR, local radiotherapy, and bortezomib chemotherapy with dexamethasone, as in this case, can be considered a safe and effective approach in cases of GPs limited to mucosa; with follow-up and endoscopic monitoring as indicated.
ISSN:0973-1482
1998-4138
DOI:10.4103/jcrt.JCRT_434_18